Recent studies seek to prove that the act of lying is not something that can be helped. Studies suggest that lying is tied to a biological component and "If someone lies repeatedly, they no longer have an emotional response when they lie," explained Sharot. "In absence of an emotional response, they feel more comfortable and lie more." "When we lie for personal gain, our amygdala (a roughly almond-shaped mass of gray matter inside each cerebral hemisphere, involved with the experiencing of emotions) produces a negative feeling that limits the extent to which we are prepared to lie," said Tali Sharot, an associate professor of cognitive neuroscience at University College London. "However, this response fades as we continue to lie, and the more it (fades) the bigger our lies become." 
"Understanding why people are dishonest is complicated. Theories about that have been the subject of psychology and sociology books." It's hard to believe that in the 21st century with all that light that has been given, that the subject of lying is a complicated theory to be understood.
This study seeks to suggest that lying is a matter of desensitizing the brain, carving out a path within the brain that leads to further lying; causing an actual biological change in the brain that disallows the individual to have control over lying.
"In reality, of course, lying is not the fault of the brain but the person to whom the brain belongs. When someone tells a lie, he or she is not merely incorrect but deceptive. People who lie are deliberately distorting the truth and misleading someone in hopes of gain, placing their purposes above the understanding and trust of the person to whom they lie." 
"Lying is not a matter of physical law, but of moral injunction. It is less about chemistry than character. It reflects not merely what we regard as expedient in the moment but who we are at our core. Ironically, while it is less momentous to act well than to be good, we are in the end little more than the sum of all the moral compromises we have made or refused to make." 
To absolve the perplexity of the understanding of why people are dishonest, let's make it plain. "He that hath ears to hear, let him hear." Matt 11:15 KJV
True, in fact, lying is tied to a biological component but not the mysterious biology that is being linked to and accepted by modern science. Biologically, we are born in sin "... shapen in iniquity; and in sin did my mother conceive me. Psalm 51:5 KJV Lying is a sin and we have biologically been born into this condition because of the fall in Eden. At the fall, our first parents (Adam & Eve) exchanged Christ's righteousness for the lies and sins of the father of lies-Satan. "Ye are of your father the devil, and the lusts of your father ye will do. He was a murderer from the beginning, and abode not in the truth, because there is no truth in him. When he speaketh a lie, he speaketh of his own: for he is a liar, and the father of it." John 8:44 KJV ...It is impossible for God to lie. Heb 6:18 KJV
"Let no one deceive his own soul in this matter. If you harbor pride, self-esteem, a love for the supremacy, vainglory, unholy ambition, murmuring, discontent, bitterness, evil speaking, lying, deception, slandering, you have not Christ abiding in your heart, and the evidence shows that you have the mind and character of Satan, not of Jesus Christ, who was meek and lowly of heart." 
However, this condition is not without hope. Yes, sin is disease, a sickness. Yes, lying is a disease of the soul. Yes, it can be healed.
23 For all have sinned, and come short of the glory of God;
24 Being justified freely by his grace through the redemption that is in Christ Jesus:
25 Whom God hath set forth to be a propitiation through faith in his blood, to declare his righteousness for the remission of sins that are past, through the forbearance of God;
26 To declare, I say, at this time his righteousness: that he might be just, and the justifier of him which believeth in Jesus. Romans 3:23-26(KJV)
"Let no one say, I cannot remedy my defects of character. If you come to this decision, you will certainly fail of obtaining everlasting life. The impossibility lies in your own will. If you will not, then you cannot overcome. The real difficulty arises from the corruption of an unsanctified heart and an unwillingness to submit to the control of God.
To the heart that has become purified, all is changed. Transformation of character is the testimony to the world of an indwelling Christ. The Spirit of God produces a new life in the soul, bringing the thoughts and desires into obedience to the will of Christ; and the inward man is renewed in the image of God. Weak and erring men." 
..."out of the abundance of the heart the mouth speaketh." Matt. 12:34 KJV
 Testimonies to Ministers and Gospel Workers, Ellen G. White, pg.441.2
 Mind, Character and Personality Volume 2, Ellen G. White, pg. 549.3